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 The guide begins by listing an extensive array of antimicrobials, including Amoxycillin Trihydrate, Ampicillin & Cloxacillin, Benzathine penicillin, Cephalexin, Ceftriazone and Tazobactum, Levofloxacin, Oxytetracycline LA, and many others. Each drug is accompanied by details of its therapeutic group, dosage form, and specific composition.

 

For each antimicrobial, the guide outlines its indications and uses, providing valuable insights into the infections it effectively treats. From respiratory tract infections to mastitis, urinary tract infections to wound infections, and various other ailments, the guide covers a broad spectrum of conditions.

 

The recommended dosages for different animal species are clearly stated, ensuring proper administration and optimal treatment outcomes. Whether it's cattle, horses, pigs, dogs, cats, sheep, goats, or poultry, the appropriate dose is specified for each.

 

However, it's essential to be aware of potential contraindications and precautions. Hypersensitivity reactions to penicillin, renal or hepatic damage, and certain age restrictions are among the important considerations discussed in the guide.

 

Pharmaceutical precautions, such as proper storage temperatures and protection from light, are also highlighted to maintain the stability and efficacy of the medications.

 

This comprehensive guide serves as an indispensable resource for veterinary professionals and animal caregivers alike, offering valuable insights into the world of veterinary antimicrobials and their crucial role in ensuring the health and well-being of our beloved animals.

1.                    

ANTIMICROBIALS

Amoxycillin Trihydrate

Ampicillin & Cloxacillin

Benzathine penicillin

Cephalexin

Ceftriazone and Tazobactum

Levofloxacin

Oxytetracycline LA

Strepto-Penicillin

Sulphadimidine

Trimethoprim & Sulphadiazine

Ampicillin

Enrofloxacin

Amikacin

Cefotaxime

Erythromycin

Gentamycin

Metronidazole

Oxytetracycline HC

Sulphamethoxazole & Trimethoprim

Tetracycline Hydrochloride (Water soluble powder 5g/100g)

 

2.                    

ANTIMICROBIALS

Amoxycillin Trihydrate

Dosage Form: Tablet

 

Therapeutic Group: Antibacterial Agent

 

Composition: Each tablet contains an equivalent of 1.5 grams of Amoxicillin Trihydrate.

 

Indication/Use: These tablets are used to treat a variety of infections, including respiratory tract infections, mastitis, urinary tract infections, wound infections, calf scours, otitis, hemorrhagic septicemia, metritis, necrotic enteritis, infectious coryza, coli septicaemia, fowl cholera, fowl typhoid, salmonellosis, and chronic respiratory disease (CRD).

 

Dose/Administration: The recommended dosage for dogs and cats is 10 - 20mg twice daily (BID), while for cattle, horses, goats, and pigs, it is 10mg/kg of body weight twice daily (BID).

 

Contraindications: Patients with a history of hypersensitivity reactions to penicillin may experience adverse reactions.

 

Pharmaceutical Precaution: Store the tablets in a cool place, ensuring the temperature does not exceed 25°C.

 

Ampicillin & Cloxacillin

 

Drug Name: Ampicillin & Cloxacillin Injectable Solution

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Broad Spectrum Antibacterial

 

Composition: Each vial contains Ampicillin Sodium equivalent to 1gm of Ampicillin and Cloxacillin Sodium equivalent to 1gm of Cloxacillin.

 

Indication/Use: This broad spectrum amino-penicillin is indicated for the treatment of mastitis, metritis, septicemia, chronic wounds, systemic and local infections, abscesses, enteritis, and pneumonia.

 

Dose/Administration: The recommended dose is 4 - 10mg per kilogram of body weight for intramuscular (I/M) or intravenous (I/V) injection. This dose should be repeated twice daily for a period of three days.

 

Contraindications: Patients with a history of allergic reactions to penicillin should avoid using this medication.

 

Pharmaceutical Precaution: Store the injectable solution in a cool place, making sure the temperature does not exceed 25°C.

 

Benzathine penicillin

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Long-Acting Bactericidal

 

Composition: Each vial contains 48 lac (4.8 million units) and/or 6 lac (600,000 units).

 

Indication/Use:

 

- Cattle, Buffalo, Sheep, Goat: This medication is used for the treatment of actinomycosis, anthrax, blackquarter, tetanus, arthritis, mastitis, metritis, haemorrhagic septicaemia, exudative epidermitis, and pyelonephritis.

- Horse: It is indicated for the treatment of strangles, corynebacterial pneumonia of foals, and tetanus.

- Pig: This medication is used for treating swine erysipelas, tetanus, foot rot, and malignant edema.

- Dog, Cat: It is used to treat rickettsiosis, tetanus, wound infections, and respiratory tract infections.

 

Dose/Administration:

 

- Cattle, Horse, Sheep, Goat, Swine: The recommended dose is 12000 IU (international units) per kilogram of body weight. Administer deeply intramuscularly.

- Dog, Cat: The recommended dose is 40000 IU (international units) per kilogram of body weight. Administer deeply intramuscularly.

 

Precautions:

 

- This medication should only be administered deeply intramuscularly.

- Avoid using this medication in animals with a history of hypersensitivity reactions to penicillin.

 

Cephalexin

Drug Name: Cephalexin

 

Dosage Form: Tablets and Suspension

 

Therapeutic Group: Antibacterial

 

Composition: Each tablet contains 1.5gm of Cephalexin, and the suspension contains 125mg of Cephalexin in 20g powder (7.5%).

 

Indication/Use: Cephalexin is used to treat respiratory tract infections, urinary tract infections, localized infections in the skin and soft tissues, fowl cholera, gangrenous dermatitis, salmonellosis, coryza, and E. coli infections.

 

Dose/Administration:

 

- Cattle and Buffalo: The recommended dose is 5-10mg/kg body weight twice daily (BID).

- Poultry: Administer 35 - 50 mg/kg body weight orally four times daily (PO qid).

- Horses: The recommended dose is 22 - 33 mg/kg body weight orally every six hours (PO q6h).

 

Contraindications: Avoid using Cephalexin in animals with known hypersensitivity to penicillin.

 

Counseling: It is advised not to use Cephalexin simultaneously with penicillin antibiotics.

 

Pharmaceutical Precaution: Store the medication below 25°C and protect it from light.

 

Ceftriazone and Tazobactum

 

Drug Name: Ceftriazone and Tazobactam Injectable Solution

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Third Generation Cephalosporins with Semi-synthetic Beta-lactamase Inhibitor

 

Composition: Each vial contains 3g of Ceftriazone and 375mg of Tazobactam.

 

Indication/Use: This injectable solution is used for the treatment of mastitis, haemorrhagic septicemia, pneumonia, peritonitis, skin and soft tissue infections.

 

Dose/Administration:

 

- Large Animals: Administer 5 – 10 mg/kg body weight intravenously (I/V) or intramuscularly (I/M).

- Small Animals: The recommended dose is 15-25 mg/kg body weight intravenously (I/V) or intramuscularly (I/M).

- Calf, Sheep, Goat: Administer 10-15 mg/kg body weight intravenously (I/V) or intramuscularly (I/M).

Precautions: Be cautious with animals that have a known hypersensitivity reaction to penicillin, as similar reactions may occur with this medication.

 

 

Levofloxacin

Drug Name: Levofloxacin

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Quinolone Group of Antibacterial

 

Composition: Each milliliter (ml) contains 100 mg of Levofloxacin.

 

Indication/Use: Levofloxacin is indicated for the treatment of gastrointestinal infections, respiratory tract infections, genital tract infections, and skin and soft tissue infections.

 

Dose/Administration:

- Cattle: For intramuscular (I/M) administration, the recommended dose is 1.5 mg/kg body weight twice daily (BID). For intravenous (I/V) administration, the recommended dose is 5 mg/kg body weight once daily (OD).

 

Oxytetracycline LA

Drug Name: Oxytetracycline LA (Long-Acting)

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Broad Spectrum Antibacterial Agent

 

Composition: Each milliliter (ml) contains Oxytetracycline Dihydrate equivalent to 200mg of anhydrous Oxytetracycline.

 

Indication/Use: Oxytetracycline LA is indicated for the treatment and control of a wide range of common systemic, respiratory, and local infections caused by or associated with organisms sensitive to oxytetracycline in cattle, sheep, and pigs. It is effective in the therapy of acute infections caused by various organisms such as Rickettsiae, Chlamydia, Actinomycetes, Mycoplasma, protozoa, and some larger viruses.

 

Dose/Administration: The injection is given by deep intramuscular (I/M) injection to cattle, sheep, and pigs only. The recommended dosage rate is 20mg/kg body weight, for example, 1ml per 10 kg body weight. For piglets at different ages:

- Day 1: 0.2ml

- Day 7: 0.3ml

- Day 14: 0.4ml

- Day 21: 0.5ml

- Over Day 21: 1ml per 10kg body weight

The maximum volume of injection at any one site is 20ml in cattle, 10ml in pigs, and 5ml in sheep.

 

Contraindications: This medication is not to be used in dogs, cats, and horses. Once a vial has been broached, the contents should be used within 4 weeks. Do not dilute the solution (refer to literature for more details).

 

Pharmaceutical Precaution: Store the medication below 25°C and protect it from light.

 

Strepto-Penicillin

 

Drug Name: Strepto-Penicillin

 

Form: Injectable Solution

 

Therapeutic Group: Broad Spectrum Antibiotic

 

Composition: Each vial contains 2,000,000 IU of procaine penicillin and 2.5g of streptomycin sulfate.

 

Indication/Use: Strepto-Penicillin is effective against a wide variety of organisms, including Pasteurella, Klebsiella, Corynebacterium, Erysipelothrix, Listeria, Salmonella, Streptococci, and Staphylococci.

 

Dose/Administration: To prepare the solution, add 7.5ml of distilled water into the vial to make a total volume of 10ml. The recommended daily dose is 8mg of procaine penicillin and 10mg of streptomycin sulfate.

- For Large Animals: Administer 2ml per 50kg of body weight via the intramuscular (I/M) route.

- For Small Animals: Administer 1ml per 5kg of body weight via the intramuscular (I/M) route.

 

Contraindications: Avoid using Strepto-Penicillin in animals that are hypersensitive to penicillin. In case of a hypersensitive reaction, prompt treatment with antihistamines is indicated.

 

Pharmaceutical Precaution: Store the medication below 25°C and protect it from light. Use the contents within 4 weeks and ensure to shake well before use.

 

Sulphadimidine

 

Drug Name: Sulphadimidine

 

Dosage Form: Injectable Solution & Bolus

 

Therapeutic Group: Broad Spectrum Antibiotic

 

Composition: Each milliliter (ml) contains 333mg of Sulphadimidine sodium, and each bolus contains 5g of Sulphadimidine.

 

Indication/Use: Sulphadimidine is used in the treatment of infectious diseases in calves, milking cows, sheep, and pigs caused by or associated with organisms sensitive to Sulphadimidine. It is also effective in the treatment of coccidiosis and footrot.

 

Dose/Administration:

 

- For Intestinal and Caecal Coccidiosis (mainly in calves and poultry): Initial dose of 200mg/kg or 15 to 30ml/50kg, followed by a maintenance dose of 100mg/kg or 7.5 - 15ml/50kg daily, given via intravenous (I/V) or subcutaneous (S/C) route.

- For Hemorrhagic Septicemia in Cattle: S/C injection in calves and I/V in milking cows; Initial dose of 200mg/kg or 15 to 30ml/50kg, followed by a maintenance dose of 100mg/kg or 7.5 - 15ml/50kg daily, given via I/V or S/C route.

- In Dogs: Half of the initial dose should be given twice daily via I/V or S/C route.

- Horse, Cattle, Sheep, Goat & Pigs: 200mg/kg body weight, e.g., 2 boluses per 50kg body weight followed by 1 tablet/50kg daily for two further days only. The tablets can be used as uterine pessaries prophylactically in cattle after parturition and in the treatment of metritis.

 

Contraindications: Avoid using Sulphadimidine in animals with known sulphonamide sensitivity, severe liver damage, and blood dyscrasias. Do not use it via the intramuscular (I/M) route; I/V administration should be given slowly. To minimize local tissue reactions following S/C injections, divide the dose into 2 or 3 parts and inject into several sites. Prolonged treatment may lead to vitamin K deficiency, agranulocytosis, and hemolytic anemia, especially in young stock. Avoid using local anesthetics of the procaine group during treatment. Not for use in pre-ruminant calves.

 

Counseling: The bolus can be administered whole or crushed into powder form.

 

Pharmaceutical Precaution: Store the medication below 25°C and protect it from light. Use the contents within 4 weeks. Shake well before use.

 

Trimethoprim & Sulphadiazine

 

Drug Name: Trimethoprim & Sulphadiazine

 

Dosage Form: Injectable Solution, Bolus/Pessary

 

Therapeutic Group: Antibacterial Agent

 

Composition: Each milliliter (ml) contains 400mg of Sulphadiazine and 80mg of Trimethoprim. Each bolus contains 2g of Sulphadiazine and 400mg of Trimethoprim.

 

Indication/Use:

 

Oral: This medication is used for the treatment of bacterial scours in calves, sheep, and foals; systemic infections, such as acute salmonellosis, E. coli infections, bacterial pneumonia, calf diphtheria, and more; intrauterine infections after parturition and other female genital tract and alimentary infections (e.g., gastroenteritis, peritonitis); upper and lower respiratory tract and urogenital tract infections; skin infections, septicemia, eye, ear, and mouth infections, etc.

 

Dose/Administration:

 

Oral: Provide 30mg/kg/day. For foals, calves, and sheep, administer 1 bolus per 80kg of body weight orally in 2 divided doses daily for 3 days.

Intra-Uterine: For mares and cows, administer 1 to 2 boluses. For sows and ewes, administer 0.5 to 1 bolus.

By I/M Route: The standard dose for all animals is 1ml per 30kg of body weight daily.

 

Contraindications: Avoid using Trimethoprim & Sulphadiazine in animals with known sulphonamide sensitivity, liver parenchymal damage, and blood dyscrasias.

 

Pharmaceutical Precaution: Shake well before use. Store the medication below 25°C and protect it from light.

Ampicillin

 

Drug Name: Ampicillin

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Broad Spectrum Aminoglycoside Antibiotic

 

Composition: Each vial contains either 250mg or 500mg of Ampicillin Sodium.

 

Indication/Use: Ampicillin is a broad-spectrum bactericidal antibiotic effective against a wide range of Gram-positive and Gram-negative organisms, as well as many spirochetes, including Leptospira sp. It is particularly indicated for the treatment of infections in the gastrointestinal (GI) tract, respiratory system, urogenital tract, mastitis, infectious arthritis, local wounds or abscesses, septicaemia, and other related conditions.

 

Dose/Administration: Administer the medication by intramuscular (I/M) or intravenous (I/V) injection at a dose of 2 - 7mg per kilogram of body weight. Repeat the dose once or twice daily and continue as necessary at the clinician's discretion.

 

Contraindications: Avoid using Ampicillin in small herbivores (e.g., guinea pigs, rabbits, hamsters). Also, do not use it in animals with a history of allergic reactions to penicillin.

 

Pharmaceutical Precaution: Store the medication below 25°C.

 

Enrofloxacin

Drug Name: Enrofloxacin

 

Dosage Form: Tablet

 

Therapeutic Group: Fluoroquinoline Group of Antibacterial

 

Composition: Each tablet contains 150mg of Enrofloxacin.

 

Indication/Use:

 

Cattle, Buffalo, Sheep, Goat: Enrofloxacin is indicated for the treatment of acute and chronic mastitis, respiratory tract infections, pneumonia, haemorrhagic septicaemia, black quarter, pyometra, metritis, joint ill, urogenital infections, otitis, brucellosis, and salmonellosis.

 

Dog, Cat, Pig, Horse: It is used to treat respiratory tract infections, gastrointestinal infections, coli-septicaemia, wounds, urogenital infections, broncho-pneumonia, and secondary bacterial infections associated with viral diseases.

 

Poultry: Enrofloxacin is effective against CRD (chronic respiratory disease), colibacillosis, infectious coryza, pasteurellosis, salmonellosis, fowl typhoid, fowl coryza, and other mixed bacterial infections.

 

Dose/Administration:

 

For Animals: Administer a dose of 2.5 – 5 mg/kg body weight.

 

For Poultry: Mix 250 mg of Enrofloxacin per liter of drinking water.

 

Contraindications:

 

- Enrofloxacin is contraindicated in young animals below 1 year of age and cats below 8 weeks of age, as it may cause arthropathic effects.

 

- Gastrointestinal and central nervous system disturbances, as well as rashes, may be seen as adverse effects.

 

- It is not recommended for use in horses.

 

Pharmaceutical Precaution:

 

- Store the tablets in a cool place and protect them from light.

 

- Once the vial is opened, no more than 5 withdrawals should be made, and the product should be used within 28 days of the first withdrawal.

 

Amikacin

 

Amikacin is an injectable solution belonging to the therapeutic group of broad-spectrum aminoglycoside antibiotics. Each milliliter (ml) of this solution contains an equivalent of 250mg of Amikacin sulfate.

 

Indications/Uses:

Amikacin is used to treat both local and systemic infections caused by bacteria. It is effective in conditions such as septicemia (bloodstream infection), trachea-bronchitis (inflammation of the trachea and bronchi), osteoarthritis (joint inflammation), urinary tract infections (UTI), gastrointestinal (GI) infections, as well as wounds and skin infections.

 

Dosage/Administration:

The recommended dose of Amikacin is between 5 to 7.5mg per kilogram of body weight. The drug can be administered via intramuscular (I/M) or subcutaneous (S/C) route, and it should be given every 12 hours.

 

Contraindications:

Amikacin should be used with caution as it has the potential to be toxic. It may cause adverse effects such as ototoxicity (damaging to the ears), neuromuscular blockade (interference with nerve-muscle communication), and nephrotoxicity (kidney damage).

 

Counseling:

It is essential not to use Amikacin in food animals, as it may have adverse effects on their meat or milk. If used in dairy animals, their milk should be discarded for three days after the treatment.

 

Pharmaceutical Precaution:

The injectable solution should be protected from direct sunlight to maintain its potency and stability.

 

 

Cefotaxime

 

Cefotaxime is available in both injectable solution and tablet forms. It belongs to the therapeutic group of Third-generation Cephalosporins.

 

Composition:

Each vial of injectable solution contains 1g of cefotaxime, and each tablet contains 500mg of cefotaxime.

 

Indications/Uses:

Cefotaxime is used to treat various infections in animals, including:

 

1. Intra-abdominal infections

2. Urinary tract infections

3. Respiratory tract infections

4. Localized infections of the skin and soft tissues

5. Tuberculosis

 

Dosage/Administration:

For dogs and cats, the recommended dose is 25 mg/kg, given either intravenously (I/V) or intramuscularly (I/M), twice a day (BID).

 

Precautions:

It is essential to avoid using cefotaxime in animals that are sensitive to penicillin or have a known penicillin allergy.

 

Pharmaceutical Precaution:

Store cefotaxime below 25°C and protect it from light to maintain its stability and efficacy.

 

 

Erythromycin

 

Erythromycin is available in tablet form and belongs to the therapeutic group of antibacterial agents.

 

Composition:

Each tablet contains 100mg of Erythromycin stearate.

 

Indications/Uses:

Erythromycin is indicated for the treatment of various bacterial infections in different animals, including:

 

1. Bacterial pharyngitis

2. Bronchitis

3. Pneumonia

4. Amoebic dysentery

5. Sinusitis

6. Abortion

7. Brucellosis

8. Feline pneumonitis

9. Actinomyces infections

10. Mastitis

11. Urinary tract infections (UTI)

12. Pyometra

13. BQ (Bovine Quiets Disease)

14. Pink eye and Gasser's disease in horses

15. Swine erysipelas and enzootic pneumonia in pigs

16. Chronic Respiratory Disease (CRD), ornithosis, infectious synovitis, and infectious coryza in poultry.

 

Dosage/Administration:

The recommended oral dosage for different animals is as follows:

 

- Cattle, sheep, goat, and horse: 2.2 - 4.4 mg/kg body weight

- Pigs: 2.2 - 6 mg/kg body weight

- Dog: 10 - 40 mg/kg body weight

- Cat: 10 - 15 mg/kg body weight

 

Contraindications:

Large doses of erythromycin may lead to vomiting and diarrhea occasionally.

 

Pharmaceutical Precaution:

Erythromycin should be stored below 25°C and protected from light to maintain its effectiveness.

 

Gentamycin

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Narrow-Spectrum Antibacterial Agent

 

Composition: Each milliliter contains 40mg of Gentamicin sulfate.

 

Indication/Use: Gentamicin is effective in treating bacterial infections caused by susceptible organisms in dogs and cats. It is used for conditions such as urinary tract infections (UTI), cystitis, nephritis, respiratory tract infections, pneumonia, tracheobronchitis, pyodermatitis, wounds, and peritonitis.

 

Dose/Administration: Gentamicin can be administered intramuscularly (I/M) or subcutaneously (S/C). For dogs and cats, the recommended dosage is 3 - 5 mg/kg every 12 hours on the first day, followed by once-daily administration thereafter.

 

For cattle and horses, the dosage is 1 - 2 mg/kg of body weight as a parenteral injection, given 2 to 4 times daily. For intra-uterine infusion, mix 3 - 6 ml of Gentamicin with 30 - 60 ml of distilled water or normal saline and administer for 3 - 5 days. In mares, mix 40ml of Gentamicin with 200ml of sterile saline and use for 3 - 5 days.

 

Contraindications: Gentamicin should not be used in food-producing animals or pregnant animals. Reduce the dosage by half in animals with impaired renal function. Avoid using Gentamicin in combination with diuretics like Frusemide.

 

Pharmaceutical Precaution: Store Gentamicin below 25°C and protect it from light to ensure its stability and effectiveness.

 

 

Metronidazole

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Antibacterial and Antiprotozoal Agent

 

Composition: Each milliliter contains 500mg of Metronidazole.

 

Indication/Use: Metronidazole is used in the treatment of various conditions in animals, including post-partum metritis, pyometra, endometritis, abortion, repeat breeding, wound infections, hoof infections (including abscesses and thrush), sinusitis, balanitis, balanoposthitis, otitis externa, gingivitis, and anal sacculitis.

 

Dose/Administration: The recommended dosages for different conditions in cattle and buffaloes are as follows:

 

1. Intravenous: 4ml/kg body weight daily for 7 days.

2. Intra-uterine: 25-50ml every alternate day for 3 days.

3. Topical: The quantity of Metronidazole used will depend upon the nature of the lesions being treated. The treatment should continue for 7 days.

 

Pharmaceutical Precaution: Store Metronidazole below 25°C and protect it from light to maintain its stability and efficacy.

 

Oxytetracycline HCL

 

Dosage Form: Injectable Solution

 

Therapeutic Group: Broad Spectrum Antibacterial

 

Composition: Each milliliter contains a stable aqueous solution equivalent to 50mg of Oxytetracycline HCl.

 

Indication/Use: Oxytetracycline HCl is indicated for the treatment and control of a wide range of common systemic, respiratory, and local infections caused by or associated with organisms sensitive to oxytetracycline in cattle, sheep, and pigs. It is effective in treating infections caused by pathogenic bacteria, certain Rickettsiae, Chlamydia, Actinomycetes, Mycoplasma, protozoa, and some large viruses.

 

Dose/Administration: The recommended dosages for different animals are as follows:

 

- Cattle & Horses: 2 - 5mg/kg body weight (1 - 2ml/25kg) daily for 3 - 5 days.

- Pigs, Sheep & Goats: 4 - 9mg/kg body weight (2 - 2.5ml/25kg) daily for 3 - 5 days.

- Dogs & Cats: 1ml/10kg body weight daily for 3 - 5 days.

 

The medication should be administered intramuscularly (I/M) or slowly intravenously (I/V).

 

Contraindications: Oxytetracycline HCl should not be used in animals with renal or hepatic damage. In dogs, avoid the intravenous (I/V) route of administration. Dilution with solutions of calcium salts may cause precipitation and should be avoided.

 

Pharmaceutical Precaution: Store Oxytetracycline HCl in a cool, dry place and protect it from light. The solution may darken on storage, but its potency remains unaffected unless the product is expired.

 

 

Sulphamethoxazole & Trimethoprim

 

Dosage Form: Solution or Bolus

 

Therapeutic Group: Diaminopyrimidine-Potentiated Antibiotic

 

Composition: Each sachet (5g) contains 2g of Sulphamethoxazole and 400mg of Trimethoprim.

 

Indications/Use: This medication is effective in treating mixed bacterial infections that affect the gastrointestinal tract, urinary tract, and genital tract in poultry.

 

Dose/Administration:

 

For Chicks: Administer 2.5g per 100 birds. Mix this amount in 8 liters of drinking water or 25mg per bird in approximately 80ml of water.

 

For Growers and Broilers: Administer 5g per 100 birds. Mix this amount in 16 liters of drinking water or approximately 160ml per bird.

 

For Layers: Administer 10g per 100 birds. Mix this amount in 21 liters of drinking water or approximately 210ml per layer.

Tetracycline Hydrochloride (Water soluble powder 5g/100g) Dosage Form

 

Dosage Form: Water-Soluble Powder

 

Therapeutic Group: Antibacterial Agent

 

Composition: Each 100g contains 5g of Tetracycline HCl.

 

Indications/Uses: This water-soluble powder is used for the prevention and treatment of a wide variety of infections affecting the respiratory, gastrointestinal, genital, and urinary tracts in both large and small animals, as well as birds.

 

Dose/Administration: The medication is administered through drinking water. The recommended dosages are as follows:

 

- Large animals: 2.5 - 5g per 15kg of body weight.

- Small animals: 1g per kilogram of body weight.

 

For severe infections, the above dosages may be increased or doubled. In poultry, the treatment dosage is 5g mixed in 4.5 liters of drinking water. The dosage can be increased or doubled in severe cases. Treatment should be continued until 24 hours after the symptoms disappear, and during the treatment period, birds should only be given the medicated water.

 

Contraindications/Warnings: Use of tetracycline hydrochloride in late pregnancy or in neonates can cause permanent discoloration of rapidly growing teeth. The use of broad-spectrum antibiotics may lead to the overgrowth of non-susceptible organisms, particularly monilia; if new infections appear during treatment, appropriate measures should be taken. Prolonged oral antibiotic therapy in combination with a restricted diet may necessitate concurrent multivitamin supplementation.

 

Pharmaceutical Precautions: Store the water-soluble powder below 25°C.

 

Note: The information provided here is based on the details provided in the context. It is crucial to follow the dosage and administration instructions provided by a veterinarian or on the medication's packaging for safe and effective use in animals. Veterinary medications should only be used under the guidance and prescription of a qualified veterinarian.